Presentations

Day 1

Day 1: 9.30-11.00 Launch of the conference

Introductory speeches of honorary guests Chair: Dr. Tomáš Zábranský (Czech Republic) Speakers: Pavel Bém, president of the conference Dr. Svatopluk Němeček, Minister of Health of the Czech Republic, patron of the conference Prof. Jan Žaloudík, member of the Senate of the Parliament of the Czech Republic Prof. Michel Kazatchkine, The Global Commission on Drug Policy Jindřich Vobořil MA MHA, the Czech National Drug Coordinator Prof. Tomáš Zima, Rector of Charles University in Prague, chair of the Honorary Board of the Conference Prof. Raphael Mechoulam, rector emeritus, Hebrew University of Jerusalem

Day 1: 11.20-11.50 Plenary discussion

Plenary discussion organised under the auspices of the Global Commission on Drug Policy (GCoDP) Medical Marijuana vs. Devil’s Weed, Relieving Morphine vs. Smack, Ritalin for our Kids and Meth Definitely Not For Our Kids: what regulation for what – and why? Moderator: Pavel Bém (Czech Republic); The options for legal regulation of drug markets Speakers: Prof. Michel Kazatchkine (France): Supranational legislature / UN Convention and the level of freedom of individual states for securing necessary controlled medicines to patients. Steph Sherer (USA): The US federal and national legislature on medical marijuana, and controlled drugs in general: a pitfall or a space for maneuvring? Dr. Pavel Pachta (ex-INCB secretariat): The international drug control treaties and medical use of cannabis and cannabinoids - INCB approach in time Milton Romani Gerner (Uruguay): Uruguay and its legislature on medical and recreational cannabis: state of art and outlook Dr. Eberhard Pirich (Austria): The Austrian model of prescription and reimbursement of cannabinoids

Day 1: 14.00-15.15 Parallel sessions, part 2

Policy in medical cannabis and other psychoactive substances – the EU experience (Bohemia II+III) Moderator: Danillo Ballotta (European Monitoring Centre for Drugs and Drug Addictions – EMCDDA) Rapporteur: Prof. Philippe Lucas (Canada)

Day 1: 15.30-16.45 Parallel sessions

Policy in medical cannabis and other psychoactive substances – the US experience Moderator: Steph Sherer (USA) Rapporteur: Dr. Jahan Marcu (USA)

Day 1: 17.00-18.30 Plenary discussion

Medical cannabis reform in multiple legal and medical environments Medical cannabis reform in multiple legal and medical environments – different approaches, different proceedings, one goal (rapporteurs from the parallel sessions, followed by roundtable discussion with a moderator) Moderator: Dr. Vendula Běláčková (Czech Republic); Brief overview of the long story of medical cannabis in the Czech Republic Speakers: Boaz Wachtel

Day 2

Day 2: 9.00-10.30 Plenary

Cannabis and cannabinoids in medical research and medical treatment Overview of cannabis and cannabinoids in medical research and medical treatment. The state of research in the area of medical cannabis and its prospects. Chair: Prof. Raphael Mechoulam (Israel) Discussants: Dr. Yuval Landschaft (Israel): Research nd medical cannabis in the State of Israel Dr. Arno Hazekamp (Netherlands): Standardisation of CBD and THC-CBD delivery by vaporisation - protocolas and options Prof. Ethan Russo (USA): A Researcher's View on Practical Aspects and Pitfalls of Treatment with Medical Cannabis Prof. Raphael Mechoulam (Israel): Discussion overview and personal insight

Day 2: 10.50-12.20 Joint medical workshop (all specializations), part 1

Introduction into practical use of cannabis for medical doctors and nurses - part I The human endocannabinoid system and the treatment of medical symptoms. Medical cannabis and indications for medical use in Israel and elsewhere. Moderators/trainers: Dr. Yehuda Baruch (Israel - OWC), Zach Klein, Yelena Sosnovsky, DiS MedNurse (Israel)

Day 2: 13.50-15.20 Joint medical workshop (all specializations), part 2

Introduction into practical use of cannabis form medical doctors and nurses - part II Synthetic endocannabinoids: harms and medical use. Most frequent side-effects of (medical) cannabis use and how to treat them Moderators/trainers: Dr. Yehuda Baruch (Israel - OWC), Zach Klein, Yelena Sosnovsky, DiS MedNurse (Israel)

Day 2: 15.45-17.15 Joint medical workshop (all specializations), part 3

Introduction into practical use of cannabis form medical doctors and nurses - part III Various strains of medical cannabis and when to use them. Dosing of medical cannabis (how to start, how long, how and when to stop) – part 1. Moderators/trainers: Dr. Yehuda Baruch (Israel - OWC), Zach Klein, Yelena Sosnovsky, DiS MedNurse (Israel)

Day 3

Day 3: 9.00-10.30 Plenary

Ethical Issues in Treatment and Medical Research Using Medical Cannabis (hosted by better) Moderator: Pavel Kubů (Czech Republic) Speakers: Dr. Sue Sisley (USA), Dr. Ilya Reznik (Israel), Prof. Uri Kramer (Israel), Steph Sherer (USA)

Day 3: 10.50-12.45 Joint medical workshop (all specializations), part 4

Introduction into practical use of cannabis form medical doctors and nurses - part IV Dosing of medical cannabis (how to start, how long, how and when to stop) – part 2. Various ways of consumption and related equipment. Role of physicians/ role of nurses; telephone helplines and other support. Technical Guidelines for prescribing medical cannabis and preparations made of it in the Czech Republic (Czech State Agency for Medical Cannabis). Moderators/trainers: Dr. Yehuda Baruch (Israel - OWC) and Jana Venclíková (Czech Republic)

Day 3: 13.45-14.45 Parallel Medical workshops, part 1

Pain management using cannabinoids Trainer: Prof. Silviu Brill (Israel)

Day 3: 13.45-14.45 Parallel Medical workshops, part 2

Medical cannabis in palliative care Trainer: Dr. Jonathan Grunfeld (Israel) - hosted by better

Day 3: 13.45-14.45 Parallel Medical workshops, part 3

Cannabis and cannabinoids in neurology and dermatology Trainer: Dr. Támás Biró (Hungary)

Day 3: 15.05-16.40 Parallel Medical Workshops, part 1

Medical cannabis in oncology Trainer: Dr. Jonathan Grunfeld (Israel) – hosted by better

Day 3: 15.05-16.40 Parallel Medical Workshops, part 2

PTSD, Tourette sydrome and other psychiatric diagnoses for cannabis use Trainer: Dr. Sue Sisley (USA) – hosted by better

Day 3: 15.05-16.40 Parallel Medical Workshops, part 3

Cannabis and epilepsy in children and adolescents – the situation in Israel, USA, and elsewhere Trainer: Prof. Uri Kramer (Israel) – hosted by better

Day 4

Day 4: 9.00-10.30 Plenary

The advances and future directions in cannabis and cannabinoids research The use of cannabis and cannabinoids in modern medical practice. The cutting-edge research and scientific prospects in the area of medical cannabis. Moderator and rapporteur: Prof. Lumír Hanuš (Czech Republic and Israel) Speakers: Prof. Pal Pacher (USA): Key opposing regulatory role of peripheral cannabinoid CB1 and CB2 receptors in inflammatory processes, oxidative stress and tissue injury Prof. Uri Kramer (Israel): Cannabidiol for children with refractory epilepsy - The Israeli experience Prof. Ethan Russo (Israel): Researchers view on practical aspects of treatment with medical cannabis and phytocannabinoids Prof. Silviu Brill (Israel): Pain, cannabis and cannabinoids: mechanisms, use and future directions

Day 4: 10.50-12.20 Parallel sessions

Cannabinoid research in the Czech Republic – Brno team Moderator: Prof. Alexandra Šulcová (Czech Republic): "Moravian" contributions for the identification of endocannabinoid system Presenters and discussants: Dr. Vincenzo Micale (Italy): The endogenous cannabinoid system (ECS) as a potential therapeutic target in schizophrenia: preclinical and clinical evidence Dr. Jana Kučerová (Czech Republic): The cannabis and cannabinoid "self-medication" theory: animal depressive phenotype model Dr. Jan Juřica (Czech Republic): The influence of the cannabinoids on the activity of the metabolic enzymes P450 cytochrome

Day 4: 13.45-14.45 Plenary

Cannabis, cannabinoids (and alternatives) for the wellbeing of patients Moderator: Prof. Richard Rokyta (Czech Republic) Speakers: Dr. Arno Hazekamp (Netherlands): What the patients really want - the dosage and the ways of use, globally Prof. Cristina Sanchéz (Spain): Endocannabinoids, Phytocannabinoids, and Cancer Prof. David Meiri (Israel): Cannabinoids antitumor activity in humnan cancers Dr. Mark J. Rosenfeld (USA/Canada/Israel/China): Making Cannabinoids Legal & Effective, Science-Based Medicine

Day 4: 15.05-16.50 Parallel sessions

Cannabis extract - case studies and practical experiences of natural healers Moderator: prof. Lumír Hanuš (Czech Republic and Israel) Presenters and discussants: Jindřich Bayer (Czech Republic) Ted Hong (South Korea) Dušan Dvořák (Czech Republic) Bozidar Radisic (Slovenia) Patryck Pankowski (Poland) Lukáš Hurt (Czech Republic) Andrej Susnik (Slovenia)

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